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BMPR1A Mutations in Juvenile Polyposis Affect Cellular Localization

INTRODUCTION: Juvenile Polyposis (JP) is characterized by the development of hamartomatous polyps along the entire GI tract that collectively carry a significant risk of malignant transformation. Mutations in the Bone Morphogenetic Protein Receptor Type IA (BMPR1A) are known to predispose to JP. We...

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Autors principals: Howe, James R., Dahdaleh, Fadi S., Carr, Jennifer C., Wang, Donghong, Sherman, Scott K.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683109/
https://ncbi.nlm.nih.gov/pubmed/23433720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2013.01.015
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