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Clinical Significance in Oral Cavity Squamous Cell Carcinoma of Pathogenic Somatic Mitochondrial Mutations

Somatic mutations affecting the mitochondrial DNA (mtDNA) have been frequently observed in human cancers and proposed as important oncological biomarkers. However, the clinical significance of mtDNA mutations in cancer remains unclear. This study was therefore performed to explore the possible clini...

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Detalhes bibliográficos
Main Authors: Lai, Chih-Hsiung, Huang, Shiang-Fu, Liao, Chun-Ta, Chen, I-How, Wang, Hung-Ming, Hsieh, Ling-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683038/
https://ncbi.nlm.nih.gov/pubmed/23799027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065578
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