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COMT Val(158)Met Genotype Selectively Alters Prefrontal [(18)F]Fallypride Displacement and Subjective Feelings of Stress in Response to a Psychosocial Stress Challenge

Catechol-O-methyltransferase (COMT) plays an essential role in degradation of extracellular dopamine in prefrontal regions of the brain. Although a polymorphism in this gene, COMT Val(158)Met, affects human behavior in response to stress little is known about its effect on dopaminergic activity asso...

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Detalhes bibliográficos
Main Authors: Hernaus, Dennis, Collip, Dina, Lataster, Johan, Ceccarini, Jenny, Kenis, Gunther, Booij, Linda, Pruessner, Jens, Van Laere, Koen, van Winkel, Ruud, van Os, Jim, Myin-Germeys, Inez
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683024/
https://ncbi.nlm.nih.gov/pubmed/23799032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065662
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