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Tumor Endothelial Cell-Specific Drug Delivery System Using Apelin-Conjugated Liposomes

BACKGROUND: A drug delivery system specifically targeting endothelial cells (ECs) in tumors is required to prevent normal blood vessels from being damaged by angiogenesis inhibitors. The purpose of this study was to investigate whether apelin, a ligand for APJ expressed in ECs when angiogenesis is t...

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Détails bibliographiques
Auteurs principaux: Kawahara, Hiroki, Naito, Hisamichi, Takara, Kazuhiro, Wakabayashi, Taku, Kidoya, Hiroyasu, Takakura, Nobuyuki
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682998/
https://ncbi.nlm.nih.gov/pubmed/23799018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065499
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