Evaluating Amyloid-β Oligomers in Cerebrospinal Fluid as a Biomarker for Alzheimer’s Disease

The current study evaluated amyloid-β oligomers (Aβo) in cerebrospinal fluid as a clinical biomarker for Alzheimer’s disease (AD). We developed a highly sensitive Aβo ELISA using the same N-terminal monoclonal antibody (82E1) for capture and detection. CSF samples from patients with AD, mild cogniti...

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Main Authors: Hölttä, Mikko, Hansson, Oskar, Andreasson, Ulf, Hertze, Joakim, Minthon, Lennart, Nägga, Katarina, Andreasen, Niels, Zetterberg, Henrik, Blennow, Kaj
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682966/
https://ncbi.nlm.nih.gov/pubmed/23799095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066381
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