Virucidal Efficacy of Glutaraldehyde against Enteroviruses Is Related to the Location of Lysine Residues in Exposed Structures of the VP1 Capsid Protein

Glutaraldehyde (GTA) is a potent virucidal disinfectant whose exact mode of action against enteroviruses is not understood. Earlier reports showed that GTA reacts preferentially with the VP1 capsid protein of echovirus 25 and poliovirus 1 and that GTA has affinity for exposed lysine residues on prot...

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Udgivet i:Appl Environ Microbiol
Main Authors: Chambon, Martine, Archimbaud, Christine, Bailly, Jean-Luc, Gourgand, Jeanne-Marie, Charbonné, Françoise, Peigue-Lafeuille, Hélène
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Enzymology and Protein Engineering
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC368296/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15006797/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.70.3.1717-1722.2004
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