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A gene-centric analysis of activated partial thromboplastin time and activated protein C resistance using the HumanCVD focused genotyping array

Activated partial thromboplastin time (aPTT) is an important routine measure of intrinsic blood coagulation. Addition of activated protein C (APC) to the aPTT test to produce a ratio, provides one measure of APC resistance. The associations of some genetic mutations (eg, factor V Leiden) with these...

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Bibliografische gegevens
Hoofdauteurs: Gaunt, Tom R, Lowe, Gordon DO, Lawlor, Debbie A, Casas, Juan-Pablo, Day, Ian NM
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682876/
https://ncbi.nlm.nih.gov/pubmed/23188048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.242
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