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Intermittent versus Continuous Androgen Deprivation in Prostate Cancer

BACKGROUND: Castration resistance occurs in most patients with metastatic hormone-sensitive prostate cancer who are receiving androgen-deprivation therapy. Replacing androgens before progression of the disease is hypothesized to prolong androgen dependence. METHODS: Men with newly diagnosed, metasta...

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Detalhes bibliográficos
Main Authors: Hussain, Maha, Tangen, Catherine M., Berry, Donna L., Higano, Celestia S., Crawford, E. David, Liu, Glenn, Wilding, George, Prescott, Stephen, Sundaram, Subramanian Kanaga, Small, Eric Jay, Dawson, Nancy Ann, Donnelly, Bryan J., Venner, Peter M., Vaishampayan, Ulka N., Schellhammer, Paul F., Quinn, David I., Raghavan, Derek, Ely, Benjamin, Moinpour, Carol M., Vogelzang, Nicholas J., Thompson, Ian M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682658/
https://ncbi.nlm.nih.gov/pubmed/23550669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1212299
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