Structural Dynamics of the MecA-ClpC Complex: A TYPE II AAA(+) PROTEIN UNFOLDING MACHINE

The MecA-ClpC complex is a bacterial type II AAA(+) molecular machine responsible for regulated unfolding of substrates, such as transcription factors ComK and ComS, and targeting them to ClpP for degradation. The six subunits of the MecA-ClpC complex form a closed barrel-like structure, featured wi...

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Bibliographic Details
Main Authors: Liu, Jing, Mei, Ziqing, Li, Ningning, Qi, Yutao, Xu, Yanji, Shi, Yigong, Wang, Feng, Lei, Jianlin, Gao, Ning
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Molecular Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682559/
https://ncbi.nlm.nih.gov/pubmed/23595989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.458752
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