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Tubulin Polymerization-promoting Protein (TPPP/p25α) Promotes Unconventional Secretion of α-Synuclein through Exophagy by Impairing Autophagosome-Lysosome Fusion

Aggregation of α-synuclein can be promoted by the tubulin polymerization-promoting protein/p25α, which we have used here as a tool to study the role of autophagy in the clearance of α-synuclein. In NGF-differentiated PC12 catecholaminergic nerve cells, we show that de novo expressed p25α co-localize...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ejlerskov, Patrick, Rasmussen, Izabela, Nielsen, Troels Tolstrup, Bergström, Ann-Louise, Tohyama, Yumi, Jensen, Poul Henning, Vilhardt, Frederik
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682534/
https://ncbi.nlm.nih.gov/pubmed/23629650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.401174
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