Baseline-Dependent Effects of Cocaine Pre-Exposure on Impulsivity and D(2/3) Receptor Availability in the Rat Striatum: Possible Relevance to the Attention-Deficit Hyperactivity Syndrome

We have previously shown that impulsivity in rats predicts the emergence of compulsive cocaine seeking and taking, and is coupled to decreased D(2/3) receptor availability in the ventral striatum. As withdrawal from cocaine normalises high impulsivity in rats, we investigated, using positron emissio...

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Bibliographic Details
Main Authors: Caprioli, Daniele, Hong, Young T, Sawiak, Stephen J, Ferrari, Valentina, Williamson, David J, Jupp, Bianca, Adrian Carpenter, T, Aigbirhio, Franklin I, Everitt, Barry J, Robbins, Trevor W, Fryer, Tim D, Dalley, Jeffrey W
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2013
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682140/
https://ncbi.nlm.nih.gov/pubmed/23399948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.44
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