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Bioavailability of IgG Administered by the Subcutaneous Route

PURPOSE: US licensing studies of subcutaneous IgG (SCIG) calculate dose adjustments necessary to achieve area under the curve (AUC) of serum IgG vs. time on SCIG that is non-inferior to that on intravenous IgG (IVIG), within the FDA-set limit of ±20 %. The results are interpreted as showing that dif...

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Detalhes bibliográficos
Main Authors: Berger, Melvin, Jolles, Stephen, Orange, Jordan S., Sleasman, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682093/
https://ncbi.nlm.nih.gov/pubmed/23456255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-013-9876-3
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