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Selection-Driven Accumulation of Suppressor Mutants in Bacillus subtilis: The Apparent High Mutation Frequency of the Cryptic gudB Gene and the Rapid Clonal Expansion of gudB(+) Suppressors Are Due to Growth under Selection

Soil bacteria like Bacillus subtilis can cope with many growth conditions by adjusting gene expression and metabolic pathways. Alternatively, bacteria can spontaneously accumulate beneficial mutations or shape their genomes in response to stress. Recently, it has been observed that a B. subtilis mut...

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Autors principals: Gunka, Katrin, Stannek, Lorena, Care, Rachel A., Commichau, Fabian M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681913/
https://ncbi.nlm.nih.gov/pubmed/23785476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066120
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