PTEN Loss Increases PD-L1 Protein Expression and Affects the Correlation between PD-L1 Expression and Clinical Parameters in Colorectal Cancer

BACKGROUND: Programmed death ligand-1 (PD-L1) has been identified as a factor associated with poor prognosis in a range of cancers, and was reported to be mainly induced by PTEN loss in gliomas. However, the clinical effect of PD-L1 and its regulation by PTEN has not yet been determined in colorecta...

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Detalhes bibliográficos
Main Authors: Song, Minmin, Chen, Defeng, Lu, Biyan, Wang, Chenliang, Zhang, Junxiao, Huang, Lanlan, Wang, Xiaoyan, Timmons, Christine L., Hu, Jun, Liu, Bindong, Wu, Xiaojian, Wang, Lei, Wang, Jianping, Liu, Huanliang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681867/
https://ncbi.nlm.nih.gov/pubmed/23785454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065821
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