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Efficient Sensing of Infected Cells in Absence of Virus Particles by Blasmacytoid Dendritic Cells Is Blocked by the Viral Ribonuclease E(rns)

Plasmacytoid dendritic cells (pDC) have been shown to efficiently sense HCV- or HIV-infected cells, using a virion-free pathway. Here, we demonstrate for classical swine fever virus, a member of the Flaviviridae, that this process is much more efficient in terms of interferon-alpha induction when co...

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Detalhes bibliográficos
Main Authors: Python, Sylvie, Gerber, Markus, Suter, Rolf, Ruggli, Nicolas, Summerfield, Artur
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681750/
https://ncbi.nlm.nih.gov/pubmed/23785283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003412
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