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N-Terminal Phosphorylation of the Dopamine Transporter Is Required for Amphetamine-Induced Efflux

Amphetamine (AMPH) elicits its behavioral effects by acting on the dopamine (DA) transporter (DAT) to induce DA efflux into the synaptic cleft. We previously demonstrated that a human DAT construct in which the first 22 amino acids were truncated was not phosphorylated by activation of protein kinas...

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Udgivet i:PLoS Biol
Principais autores: Khoshbouei, Habibeh, Sen, Namita, Guptaroy, Bipasha, Johnson, L'Aurelle, Lund, David, Gnegy, Margaret E, Galli, Aurelio, Javitch, Jonathan A
Format: Artigo
Sprog:Inglês
Udgivet: PLOS 2004
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC368172/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15024426/
https://ncbi.nlm.nih.govhttps://doi.org/10.1371/journal.pbio.0020078
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