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Oscillatory dynamics of Cdc42 GTPase in the control of polarized growth

Cells promote polarized growth by activation of Rho-family protein Cdc42 at the cell membrane. We combined experiments and modeling to study bipolar growth initiation in fission yeast. Concentrations of a fluorescent marker for active Cdc42, Cdc42 protein, Cdc42-activator Scd1, and scaffold protein...

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Main Authors: Das, Maitreyi, Drake, Tyler, Wiley, David, Buchwald, Peter, Vavylonis, Dimitrios, Verde, Fulvia
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681419/
https://ncbi.nlm.nih.gov/pubmed/22604726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1218377
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