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Relaxed imprinting of IGF2 in peripheral blood cells of patients with a history of prostate cancer

BACKGROUND: Insulin-like growth factor 2 (IGF2) is the predominant IGF in adults and regulates cell growth. In contrast to normal tissues, where IGF2 is imprinted and only expressed from the paternal allele, loss of imprinting (LOI) and biallelic IGF2 expression are observed in many cancers includin...

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Detaylı Bibliyografya
Asıl Yazarlar: Belharazem, Djeda, Kirchner, Matthias, Geissler, Franziska, Bugert, Peter, Spahn, Martin, Kneitz, Burkhard, Riedmiller, Hubertus, Sauer, Christian, Küffer, Stefan, Trojan, Lutz, Bolenz, Christian, Michel, Maurice Stephan, Marx, Alexander, Ströbel, Philipp
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioScientifica 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681323/
https://ncbi.nlm.nih.gov/pubmed/23781309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-12-0054
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