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Association of deletion allele of insertion/deletion polymorphism in α2B adrenoceptor gene and hypertension with or without type 2 diabetes mellitus

BACKGROUND: Vascular α2B-adrenoreceptors have the potential to increase blood pressure by mediating vasoconstriction. A nine-nucleotide deletion in the receptor enhances vasoconstriction and exacerbates hypertension. The aim of this study was to determine the association between insertion/deletion (...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tayel, Safaa I, Khader, Heba F, El-Helbawy, Nesreen G, Ibrahim, Waleed A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681199/
https://ncbi.nlm.nih.gov/pubmed/23776387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TACG.S33814
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