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Alpha(1)-antitrypsin deficiency: a clinical-genetic overview
Severe α(1)-antitrypsin deficiency (AATD) is an inherited disorder, leading to development of emphysema in smokers at a relatively young age with disability in their forties or fifties. The emphysema results from excessive elastin degradation by neutrophil elastase as a result of the severe deficien...
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| Main Authors: | , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Dove Medical Press
2011
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3681178/ https://ncbi.nlm.nih.gov/pubmed/23776367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TACG.S10604 |
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