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Disorders caused by chromosome abnormalities

Many human genetic disorders result from unbalanced chromosome abnormalities, in which there is a net gain or loss of genetic material. Such imbalances often disrupt large numbers of dosage-sensitive, developmentally important genes and result in specific and complex phenotypes. Alternately, some ch...

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Bibliografiske detaljer
Main Authors: Theisen, Aaron, Shaffer, Lisa G
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681172/
https://ncbi.nlm.nih.gov/pubmed/23776360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TACG.S8884
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