Proto-oncogenic isoform A2 of eukaryotic translation elongation factor eEF1 is a target of miR-663 and miR-744

BACKGROUND: Eukaryotic translation elongation factor 1A2 (eEF1A2) is a known proto-oncogene. We proposed that stimulation of the eEF1A2 expression in cancer tissues is caused by the loss of miRNA-mediated control. METHODS: Impact of miRNAs on eEF1A2 at the mRNA and protein levels was examined by qPC...

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Detalhes bibliográficos
Main Authors: Vislovukh, A, Kratassiouk, G, Porto, E, Gralievska, N, Beldiman, C, Pinna, G, El'skaya, A, Harel-Bellan, A, Negrutskii, B, Groisman, I
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681015/
https://ncbi.nlm.nih.gov/pubmed/23695020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.243
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