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Absence of some common organ-specific and non-organ-specific autoimmunity in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy

BACKGROUND: Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is a rare autosomal recessive disorder caused by mutations of the autoimmune regulator (AIRE) gene, whose loss of function leads to the escape of self-reactive T cells from the thymus and autoimmunity. APECED patient...

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Detalhes bibliográficos
Main Authors: Kluger, Nicolas, Krohn, Kai, Ranki, Annamari
Formato: Artigo
Idioma:Inglês
Publicado em: BioScientifica 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680957/
https://ncbi.nlm.nih.gov/pubmed/23781320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-12-0074
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