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Antioxidant enzyme, 3-mercaptopyruvate sulfurtransferase-knockout mice exhibit increased anxiety-like behaviors: a model for human mercaptolactate-cysteine disulfiduria

Human mercaptolactate-cysteine disulfiduria (MCDU) was first recognized and reported in 1968. Most cases of MCDU are associated with mental retardation, while the pathogenesis remains unknown. To investigate it, we generated homozygous 3-mercaptopyruvate sulfurtransferase (MST: EC 2.8.1.2) knockout...

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Detalhes bibliográficos
Main Authors: Nagahara, Noriyuki, Nagano, Masatoshi, Ito, Takaaki, Shimamura, Kenji, Akimoto, Toshio, Suzuki, Hidenori
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680806/
https://ncbi.nlm.nih.gov/pubmed/23759691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01986
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