Attenuation of insulin signalling contributes to FSN-1-mediated regulation of synapse development

A neuronal F-box protein FSN-1 regulates Caenorhabditis elegans neuromuscular junction development by negatively regulating DLK-mediated MAPK signalling. In the present study, we show that attenuation of insulin/IGF signalling also contributes to FSN-1-dependent synaptic development and function. Th...

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Main Authors: Hung, Wesley L, Hwang, Christine, Gao, ShangBang, Liao, Edward H, Chitturi, Jyothsna, Wang, Ying, Li, Hang, Stigloher, Christian, Bessereau, Jean-Louis, Zhen, Mei
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680742/
https://ncbi.nlm.nih.gov/pubmed/23665919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.91
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