HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment

Telomeres are repetitive DNA structures that, together with the shelterin and the CST complex, protect the ends of chromosomes. Telomere shortening is mitigated in stem and cancer cells through the de novo addition of telomeric repeats by telomerase. Telomere elongation requires the delivery of the...

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Main Authors: Kappei, Dennis, Butter, Falk, Benda, Christian, Scheibe, Marion, Draškovič, Irena, Stevense, Michelle, Novo, Clara Lopes, Basquin, Claire, Araki, Masatake, Araki, Kimi, Krastev, Dragomir Blazhev, Kittler, Ralf, Jessberger, Rolf, Londoño-Vallejo, J Arturo, Mann, Matthias, Buchholz, Frank
Formato: Artigo
Idioma:Inglês
Publicado: European Molecular Biology Organization 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680732/
https://ncbi.nlm.nih.gov/pubmed/23685356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.105
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