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Tissue-specific enhancer of the human glycoprotein hormone alpha-subunit gene: dependence on cyclic AMP-inducible elements.

We identified and characterized elements which confer tissue specificity and cyclic AMP (cAMP) responsiveness to the human glycoprotein alpha-subunit gene. An enhancer containing an 18-base-pair repeat conferred cAMP responsiveness in a non-tissue-specific fashion. DNase I protection assays revealed...

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Publicat a:Mol Cell Biol
Autors principals: Delegeane, A M, Ferland, L H, Mellon, P L
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1987
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC368068/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2828923/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.11.3994-4002.1987
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