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Angiotensin II activates NF-κB through AT(1A) receptor recruitment of β-arrestin in cultured rat vascular smooth muscle cells

Activation of the angiotensin type 1A receptor (AT(1A)R) in rat aorta vascular smooth muscle cells (RASMC) results in increased synthesis of the proinflammatory enzyme cyclooxygenase-2 (COX-2). We previously showed that nuclear localization of internalized AT(1A)R results in activation of transcript...

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Detalhes bibliográficos
Main Authors: Morinelli, Thomas A., Lee, Mi-Hye, Kendall, Ryan T., Luttrell, Louis M., Walker, Linda P., Ullian, Michael E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680646/
https://ncbi.nlm.nih.gov/pubmed/23576578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00235.2012
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