Cdk9 phosphorylates Pirh2 protein and prevents degradation of p53 protein

Several reports have pointed to the negative involvement of p53 in transcriptional regulation of the human immunodeficiency virus type 1 long-terminal repeat (HIV-1 LTR). We recently demonstrated that through their physical interaction, cdk9 phosphorylates p53 on Ser-392, leading to p53 stability an...

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Bibliographische Detailangaben
Hauptverfasser: Bagashev, Asen, Fan, Shongshan, Mukerjee, Ruma, Claudio, Pier Paolo, Chabrashvili, Tinatin, Leng, Roger P., Benchimol, Samuel, Sawaya, Bassel E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2013
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Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680536/
https://ncbi.nlm.nih.gov/pubmed/23603988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24733
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