Genomics-Guided Analysis of NAD Recycling Yields Functional Elucidation of COG1058 as a New Family of Pyrophosphatases

We have recently identified the enzyme NMN deamidase (PncC), which plays a key role in the regeneration of NAD in bacteria by recycling back to the coenzyme the pyridine by-products of its non redox consumption. In several bacterial species, PncC is fused to a COG1058 domain of unknown function, hig...

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Autors principals: Cialabrini, Lucia, Ruggieri, Silverio, Kazanov, Marat D., Sorci, Leonardo, Mazzola, Francesca, Orsomando, Giuseppe, Osterman, Andrei L., Raffaelli, Nadia
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680494/
https://ncbi.nlm.nih.gov/pubmed/23776507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065595
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