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Hypo- and Hyperglycemia Impair Endothelial Cell Actin Alignment and Nitric Oxide Synthase Activation in Response to Shear Stress

Uncontrolled blood glucose in people with diabetes correlates with endothelial cell dysfunction, which contributes to accelerated atherosclerosis and subsequent myocardial infarction, stroke, and peripheral vascular disease. In vitro, both low and high glucose induce endothelial cell dysfunction; ho...

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Main Authors: Kemeny, Steven Frank, Figueroa, Dannielle Solomon, Clyne, Alisa Morss
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680428/
https://ncbi.nlm.nih.gov/pubmed/23776627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066176
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