Transplantation of Melanocytes Obtained from the Skin Ameliorates Apomorphine-Induced Abnormal Behavior in Rodent Hemi-Parkinsonian Models

Tyrosinase, which catalyzes both the hydroxylation of tyrosine and consequent oxidation of L-DOPA to form melanin in melanocytes, is also expressed in the brain, and oxidizes L-DOPA and dopamine. Replacement of dopamine synthesis by tyrosinase was reported in tyrosine hydroxylase null mice. To exami...

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Bibliographic Details
Main Authors: Asanuma, Masato, Miyazaki, Ikuko, Diaz-Corrales, Francisco J., Higashi, Youichirou, Namba, Masayoshi, Ogawa, Norio
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680415/
https://ncbi.nlm.nih.gov/pubmed/23776585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065983
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