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Heat shock protein 70-binding protein 1 is highly expressed in high-grade gliomas, interacts with multiple heat shock protein 70 family members, and specifically binds brain tumor cell surfaces

Chaperone proteins and heat shock proteins (HSP) are essential components of cellular protein folding systems under normal conditions; their expression and activities are upregulated during stress. Chronically stressed tumors frequently exhibit high chaperone protein levels, exploiting their anti-ap...

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Autors principals: Graner, Michael W., Raynes, Deborah A., Bigner, Darell D., Guerriero, Vince
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680099/
https://ncbi.nlm.nih.gov/pubmed/19659607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2009.01269.x
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