Wird geladen...

Modeling mutant phenotypes and oscillatory dynamics in the Saccharomyces cerevisiae cAMP-PKA pathway

Background The cyclic AMP-Protein Kinase A (cAMP-PKA) pathway is an evolutionarily conserved signal transduction mechanism that regulates cellular growth and differentiation in animals and fungi. We present a mathematical model that recapitulates the short-term and long-term dynamics of this pathway...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Gonzales, Kevin, Kayıkçı, Ömür, Schaeffer, David G, Magwene, Paul M
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679983/
https://ncbi.nlm.nih.gov/pubmed/23680078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-40
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!