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Comparative analysis of 4C-Seq data generated from enzyme-based and sonication-based methods

BACKGROUND: Circular chromosome conformation capture, when coupled with next-generation sequencing (4C-Seq), can be used to identify genome-wide interaction of a given locus (a “bait” sequence) with all of its interacting partners. Conventional 4C approaches used restriction enzyme digestion to frag...

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Detalhes bibliográficos
Main Authors: Gao, Fan, Wei, Zong, Lu, Wange, Wang, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679908/
https://ncbi.nlm.nih.gov/pubmed/23705979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-345
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