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The wake-promoting transmitter histamine preferentially enhances alpha-4 subunit-containing GABA(A) receptors
Histamine is an important wake-promoting neurotransmitter that activates seven-transmembrane G-protein coupled histamine receptors. However, histamine demonstrates target promiscuity, including direct interaction with the structurally unrelated glutamate (NMDA) and GABA(A) receptor channels. Previou...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679895/ https://ncbi.nlm.nih.gov/pubmed/21640733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2011.05.020 |
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