In vitro susceptibility to quinine and microsatellite variations of the Plasmodium falciparum Na(+)/H(+) exchanger transporter (Pfnhe-1) gene in 393 isolates from Dakar, Senegal

BACKGROUND: Although the World Health Organization recommends replacing quinine (QN) by artesunate due to its increased efficacy and the higher tolerance to the drug in both adults and children, QN remains a first-line treatment for severe malaria, especially in Africa. Investigations of microsatell...

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Autores principales: Pascual, Aurélie, Fall, Bécaye, Wurtz, Nathalie, Fall, Mansour, Camara, Cheikhou, Nakoulima, Aminata, Baret, Eric, Diatta, Bakary, Fall, Khadidiatou Ba, Mbaye, Pape Saliou, Diémé, Yaya, Bercion, Raymond, Bogreau, Hervé, Briolant, Sébastien, Rogier, Christophe, Wade, Boubacar, Pradines, Bruno
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679854/
https://ncbi.nlm.nih.gov/pubmed/23758769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-12-189
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