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A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability.

The poly(A)-binding protein (PAB) gene of Saccharomyces cerevisiae is essential for cell growth. A 66-amino acid polypeptide containing half of a repeated N-terminal domain can replace the entire protein in vivo. Neither an octapeptide sequence conserved among eucaryotic RNA-binding proteins nor the...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Sachs, A B, Davis, R W, Kornberg, R D
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 1987
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367964/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3313012/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.9.3268
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