Kinetochores Coordinate Pericentromeric Cohesion and Early DNA Replication by Cdc7-Dbf4 Kinase Recruitment

Centromeres play several important roles in ensuring proper chromosome segregation. Not only do they promote kinetochore assembly for microtubule attachment, but they also support robust sister chromatid cohesion at pericentromeres and facilitate replication of centromeric DNA early in S phase. Howe...

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Autors principals: Natsume, Toyoaki, Müller, Carolin A., Katou, Yuki, Retkute, Renata, Gierliński, Marek, Araki, Hiroyuki, Blow, J. Julian, Shirahige, Katsuhiko, Nieduszynski, Conrad A., Tanaka, Tomoyuki U.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679449/
https://ncbi.nlm.nih.gov/pubmed/23746350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.05.011
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