FGF21 mediates the lipid metabolism response to amino acid starvation

Lipogenic gene expression in liver is repressed in mice upon leucine deprivation. The hormone fibroblast growth factor 21 (FGF21), which is critical to the adaptive metabolic response to starvation, is also induced under amino acid deprivation. Upon leucine deprivation, we found that FGF21 is needed...

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Main Authors: De Sousa-Coelho, Ana Luísa, Relat, Joana, Hondares, Elayne, Pérez-Martí, Albert, Ribas, Francesc, Villarroya, Francesc, Marrero, Pedro F., Haro, Diego
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2013
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Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679382/
https://ncbi.nlm.nih.gov/pubmed/23661803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M033415
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