Adam8 Limits the Development of Allergic Airway Inflammation in Mice

To determine whether a disintegrin and a metalloproteinase-8 (Adam8) regulates allergic airway inflammation (AAI) and airway hyper-responsiveness (AHR), we compared AAI and AHR in wild type (WT) versus Adam8(−/−) mice in different genetic backgrounds sensitized and challenged with ovalbumin (OVA) or...

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Main Authors: Knolle, Martin D., Nakajima, Takahiro, Hergrueter, Anja, Gupta, Kushagra, Polverino, Francesca, Craig, Vanessa J., Fyfe, Susanne E., Zahid, Muhammad, Permaul, Perdita, Cernadas, Manuela, Montano, Gilbert, Tesfaigzi, Yohannes, Sholl, Lynette, Kobzik, Lester, Israel, Elliot, Owen, Caroline A.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679335/
https://ncbi.nlm.nih.gov/pubmed/23670189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202329
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