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Glia maturation factor-γ negatively modulates TLR4 signaling by facilitating TLR4 endocytic trafficking in macrophages

TLR4 signaling must be tightly regulated to both provide effective immune protection and avoid inflammation-induced pathology. Thus, the mechanisms that negatively regulate the TLR4-triggered inflammatory response are of particular importance. Glia maturation factor-γ (GMFG), a novel actin depolymer...

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Bibliografiske detaljer
Main Authors: Aerbajinai, Wulin, Lee, Kevin, Chin, Kyung, Rodgers, Griffin P.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679304/
https://ncbi.nlm.nih.gov/pubmed/23677465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203048
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