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Post-Translational Regulation of a Hypoxia-Responsive VEGF Plasmid for the Treatment of Myocardial Ischemia

Vascular Endothelial Growth Factor (VEGF) gene therapy to promote therapeutic angiogenesis has been advanced as an alternative treatment for myocardial ischemia. The unregulated expression of VEGF and the use of viral vectors, however, have slowed the clinical development of angiogenic gene therapy....

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Detalhes bibliográficos
Main Authors: Won, Young-Wook, McGinn, Arlo N., Lee, Minhyung, Nam, Kihoon, Bull, David A., Kim, Sung Wan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679269/
https://ncbi.nlm.nih.gov/pubmed/23714244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.04.061
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