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Misfolding of galactose 1-phosphate uridylyltransferase can result in type I galactosemia

Type I galactosemia is a genetic disorder that is caused by the impairment of galactose-1-phosphate uridylyltransferase (GALT; EC 2.7.7.12). Although a large number of mutations have been detected through genetic screening of the human GALT (hGALT) locus, for many it is not known how they cause thei...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: McCorvie, Thomas J, Gleason, Tyler J, Fridovich-Keil, Judith L, Timson, David J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679265/
https://ncbi.nlm.nih.gov/pubmed/23583749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2013.04.004
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