Global Profiling in Vestibular Schwannomas Shows Critical Deregulation of MicroRNAs and Upregulation in Those Included in Chromosomal Region 14q32

BACKGROUND: Vestibular schwannomas are benign tumors that arise from Schwann cells in the VIII cranial pair and usually present NF2 gene mutations and/or loss of heterozygosity on chromosome 22q. Deregulation has also been found in several genes, such as ERBB2 and NRG1. MicroRNAs are non-coding RNAs...

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Hauptverfasser: Torres-Martin, Miguel, Lassaletta, Luis, de Campos, Jose M., Isla, Alberto, Gavilan, Javier, Pinto, Giovanny R., Burbano, Rommel R., Latif, Farida, Melendez, Barbara, Castresana, Javier S., Rey, Juan A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679163/
https://ncbi.nlm.nih.gov/pubmed/23776562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065868
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