The rat elastase I regulatory element is an enhancer that directs correct cell specificity and developmental onset of expression in transgenic mice.

A total of 134 base pairs of the 5' flanking sequence of the elastase I gene is sufficient and necessary to direct expression of the passive human growth hormone gene (hGH) to the exocrine pancreas. We demonstrate that this elastase I regulatory region contains a transcriptional enhancer which...

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Hauptverfasser: Hammer, R E, Swift, G H, Ornitz, D M, Quaife, C J, Palmiter, R D, Brinster, R L, MacDonald, R J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1987
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC367915/
https://ncbi.nlm.nih.gov/pubmed/3670302
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