Codon replacement in the PGK1 gene of Saccharomyces cerevisiae: experimental approach to study the role of biased codon usage in gene expression.

The coding sequences of genes in the yeast Saccharomyces cerevisiae show a preference for 25 of the 61 possible coding triplets. The degree of this biased codon usage in each gene is positively correlated to its expression level. Highly expressed genes use these 25 major codons almost exclusively. A...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Hoekema, A, Kastelein, R A, Vasser, M, de Boer, H A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367910/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2823108/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.8.2914-2924.1987
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