Ligand Binding and Signaling of Dendritic Cell Immunoreceptor (DCIR) Is Modulated by the Glycosylation of the Carbohydrate Recognition Domain

C-type lectins are innate receptors expressed on antigen-presenting cells that are involved in the recognition of glycosylated pathogens and self-glycoproteins. Upon ligand binding, internalization and/or signaling often occur. Little is known on the glycan specificity and ligands of the Dendritic C...

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Main Authors: Bloem, Karien, Vuist, Ilona M., van der Plas, Arend-Jan, Knippels, Léon M. J., Garssen, Johan, García-Vallejo, Juan J., van Vliet, Sandra J., van Kooyk, Yvette
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679074/
https://ncbi.nlm.nih.gov/pubmed/23776650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066266
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