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Expression of bcr and bcr-abl fusion transcripts in normal and leukemic cells.

The translocation of the c-abl oncogene from chromosome 9 to the bcr gene on chromosome 22 in cases of Philadelphia chromosome-positive chronic myelogenous leukemia (CML) generates an aberrant bcr-abl fusion transcript which may be intimately related to the pathogenesis of CML. Because factors contr...

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Bibliografiske detaljer
Main Authors: Collins, S, Coleman, H, Groudine, M
Format: Artigo
Sprog:Inglês
Udgivet: 1987
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC367905/
https://ncbi.nlm.nih.gov/pubmed/3670297
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