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From somatostatin to octreotide LAR: evolution of a somatostatin analogue

BACKGROUND: Acromegaly is characterized by overproduction of growth hormone (GH) by the pituitary gland. GH stimulates the synthesis of insulin-like growth factor-I (IGF-I), and the somatic growth and metabolic dysfunction that characterize acromegaly are a consequence of elevated GH and IGF-I level...

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Detalhes bibliográficos
Main Authors: Anthony, Lowell, Freda, Pamela U.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678951/
https://ncbi.nlm.nih.gov/pubmed/19842996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1185/03007990903328959
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